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ƿ ...賭 񸸾 丮
Ȱ 2020-02-20 06:20:52
ƿ ...賭 񸸾 丮
Ȱ 2020-02-20 06:20:52
[DP] 񸸾 úƮ 䵿

10⸸ 1õ ... Ǵٽ ٶ



[ϸ=Ȱ ] 10Ⱓ ġ Ҵ. 1 'ƿ' 2010 ۿ Ǹ鼭 ڸ ä 鰣 Ż ġߴ. ' ġ ü߰ ȿ پ ϴ' ǰ ϰ, 索 ġ 뷮 ٲ '輾' ġ ó Ȱ⸦ ã ̴.

׷ '' Ϲߺ ö 鼭 . Ѷ ָ ǰ ޾ ߸ 鼭 ü 𸥴ٴ 尨 . ݻ ǰ ɵ .

ߺ񸸽 10⸸ Ըȸ...''

20 Ǿǰ ťƿ 3б ġ Ը 354 ⵿ 45.4% þ. 2017 4б ¼ ϸ鼭 2 70% ̻ Ȯƴ. 3б Ը 1009̴. 2009 10⸸ ó 1000 Ѿ.

ϵ '' ̾ ƿƼ 'Ʈ'(и ǿ/Ʈ) ߸ϴ ۷ι 簡 񸸽ž ϰ, ģ ̾ GLP-1 索 ġ 뷮 ٲ '輾' ϸ鼭 ⼼ ȸߴٴ м̴.

  2010-2019 ġ б⺰ (: , ڷ: ť)

׷ ó Ȱ⸦ ã ġ 忡 ٽñ ο ׸ڰ 帮. Ѷ ġ 1 ö ''(и ī) 鼭.

̱ǰǾǰ(FDA) 13(ð) ߻ ̿ '' ö ûߴ. ȯ 12000 CAMELLIA-TIMI 61 ӻ󿡼 ߺ Ұ ƴٴ .

CAMELLIA-TIMI 61 ȿ Ϸ ȹ ۷ι ӻ̴. 2014 1 2015 11 8 473 Ƿ 2 索 ڸ 12000 Ǵ ູ뱺 ο ɱٰ, ߰ ֿ(MACE) ߻ ߴ.

2 ȸ(ESC 2018) ø ص 뱺 MACE ߻ 6.1%, ౺(6.2%) 񿭵 ߴٴ ǥϸ鼭 ȭߴٴ 򰡸 ޾Ҵ.

  2018 ױ۷ο޵ſ ǥ CAMELLIA-TIMI 61 (ڷ: NEJM 2018;379:1107-1117)

FDA 2018 6 Ⱓ ø ֽ м 뱺 ߾ ߻(462, 7.7%) ౺(423, 7.1%) Ÿ. 뱺 , , Ϻ ߻ Ұ, ġⰣ Ҽ ౺ ߻ ̰ ϴ .

FDA Ƿ鿡 " ó ﰢ ߴؾ Ѵ. ȯڵ鿡 ӻ ߻ ˸, ߴϵ ġ϶" ǰߴ. ٸ Ѵٰ , ߴٴ ˻(screening) ʿ ٴ ̴.

FDA ̰ ġ 嵵 ߴ. '' ǸŸ ϴ ϵ ǰǾǰó Ǹų óߴܰ ϱ⿡ ռ XR 2 ǰ Ǹߴ ȴ.

ľó "ī Ǿǰ ؼ( ߻ ) ͼ(ü ) ȸϴ Ǵܵȴ" Ǹ Բ ȸ⸦ ߴ.

߽úƮ ȭ...

븦 Ҵ 񸸾 ó ƴϴ. ġ ָҴ Ŀ 'úƮ' Ǿǰ 2010 9 ġ .

úƮ 2010 1 Ǿǰû(EMA) ֺƮ 2003 9880 ӻ 'ƿ'(и úƮ) ȯ 11.4% ߴٴ Ǹߴ ϸ鼭 ˹ߵƴ.

ľó EMA ġ úƮ ó ϰ 忡 ܷ ߴµ, 10 ̱ FDA "úƮ ͼ ʰѴٰ Ǵܵ ʴ´" Ǹű ȴ.

  ( ð ) úƮ ƿ, , ũ, , Ŀ, ú彺 ǰ

'ƿ' ѹ̾ǰ '', 'Ŀ', ٴ 'ũ', '', Ѿ 'Ÿ' 39 60 ǰ ź Ծ.

ť б⺰ ġ Ը 2009 2б 282 úƮ Ǿǰ ް 2011 2б 139 丷. úƮ 鸸ŭ Ը ̴.

̹ úƮ 'Ÿ' , ġ óߴܵƴ. ͹ΰ ÷ Բ ϴ '-' Ǹ̻ ۿ FDAκ , Ǹű ó ޾Ҵ.

͹, Ʈ żǾǰ ȯ, ﰨ ۿ ߻ ̴.

ν ؾ 'Į(и øƮ)' Ѷ 츮 ̱ ̾ 2 ŭ α⸦ , ջ 뼺 Ÿ ؾ Ѵٴ 弼 .

Ϸ ´ 츮 忡 'ȿ ġ' Ű. FDA ġ 㰡ϴ 5% ̻ ü߰ ȿ ӻ ܿ ߰ ӻ ๰ ȿ ϵ 䱸ϸ鼭 㰡 ȭϱ⿡ ̸.
Ȱ (kjan@dailypharm.com) ٸ
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ݱ

Ǹ ͸ , Ǹ ̸ ̵ ˴ϴ. ͸ ʸ ϸ, ͸ մϴ.

ο ø Ϲȸ ϴܿ ǽð ˴ϴ.

뺸 ϰ ̵ ̿ Ǵ ֽϴ.

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    弳 , Ӿ

    Ź, ɿ ˵Ǵ ( û )

    Ư ̳ ü ϴ

    Ư ѼϿ ش ûϴ

    Ư (ֹεϹȣ, ȭ, ּ ) Խϴ

    Ÿ ID Ȥ г ϴ

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    ۱ڷκ , , ϴ

    Ÿ ʻ ħϰų ϴ

    翡 ̿ (Ÿ ID, йȣ )

  • ̻ Ϻ ׿ ̿ 縦 , Ρ ó ֽϴ.

    õ ̴ ҹ Ǵܵǰų ϸ 񽺿 ٶ ʴٰ ǴܵǴ ġ ϰڽϴ.

    رŸ ϸ ڿ ֽʽÿ. ּҴ dailypharm@dailypharm.comԴϴ.

ֽż ݴ
  • 2020.02.20 10:47:19

    ְ ְ

    Һڵ 屸 ̿Ͽ ϰ ׵ ܹ Ծ

    0 0 0
ٺ Ϲݾ ǸŰ (2024 10)
õ- ౹ 32
ǰ ְ
ѽŻ÷(10) 3,500 2,500 1,000 2,901
޾(100) 24,000 22,000 2,000 22,667
Ʒγΰ(100) 30,000 28,000 2,000 29,108
īɾ(10g) 8,000 6,500 1,500 6,850
Ľõ򿬰(5g) 5,500 4,500 1,000 5,177
Ź(4) 4,500 4,000 500 4,117
ڶ(20) 6,500 6,000 500 650
(10) 5,500 4,500 1,000 4,845
Ժ(10) 4,000 3,000 1,000 3,457
ڱ׸(20) 5,000 4,000 1,000 4,567
ť(10) 3,500 2,500 1,000 2,741
Ȱť(1) 1,200 1,000 200 1,172
Ǯɾ(3.3ml) 25,000 25,000 0 25,000
޵𿬰(10g) 7,000 6,000 1,000 6,272
öŸ(34) 12,500 11,000 1,500 11,481
뽺ī(20g) 22,000 18,000 4,000 20,372
ġ(1) 1,500 1,000 500 1,078
ӽ÷(21) 10,000 8,000 2,000 9,014
ͺ(10) 3,500 3,000 500 3,189
ݿ(1ڽ) 3,000 3,000 0 3,000
׶÷糪ƮŸ(6) 8,000 7,000 1,000 7,926
߽Ÿ(120) 70,000 40,000 30,000 49,333
Źĸ(10ĸ) 3,000 2,500 500 2,943
Ÿ̾(120) 60,000 45,000 15,000 51,200
տ(60ĸ) 30,000 24,000 6,000 27,100
Ÿ̷ER(6) 3,000 3,000 0 3,000
ٿ(30g) 12,000 10,000 2,000 11,421
(120) 25,000 20,000 5,000 23,409
Ʒ(6) 4,000 3,000 1,000 3,385
ǽõĸ(270ĸ) 110,000 100,000 10,000 101,667
B(120) 60,000 60,000 0 60,000
׳(10) 3,000 3,000 0 3,000
6̺(10) 3,000 2,500 500 2,947
(60) 200,000 200,000 0 200,000
Ⱦ 12,000 10,000 2,000 10,550
̰źĸ(60ĸ) 25,000 22,000 3,000 23,087
Ųť(20) 5,500 4,500 1,000 4,722
λ絹÷(100) 35,000 30,000 5,000 31,951
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ּ: ı 128 SK V1 GL ƮνƼ A 401ȣ
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